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Longo, D

Article Highlights Weight loss agents in the glucagon-like peptide 1 receptor and FGF21 group induced a rapid suppression of leptin immediately upon agonist exposure

A framework like this is a quiet standard for what GLP-1 care should look like

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These GLP-1s include prescription drugs like Ozempic and Wegovy, which have the active ingredient semaglutide, Trulicity, which contains dulaglutide, and Zepbound and Mounjaro which are newer tirzepatides

This might mean extending the time at each dose level to 6-8 weeks instead of 4, allowing more time to assess both tolerability and disease activity at each level