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Description
It's also important to note that these medications carry a boxed warning for risk of thyroid C-cell tumors and are contraindicated in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)
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E&OE The author was formerly executive director of Indian Journal of Clinical Practice in an era when there were only JAMA and BMJ as the leading medical journals available for Indian clinicians

the documented protocol is monotherapy
In brief, male mice were deeply anaesthetized with an intraperitoneal injection of 7% chloral hydrate and transcardially perfused with a modified ice-cold artificial cerebrospinal fluid (aCSF) (described below)
Flannery PJ, Trushina E