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2.1.1 Effects on lipid structure and on the liver The SURPASS-2, where TZP (with metformin) was compared to semaglutide (74, 88), showed adjunctive effects, such as lowering the concentrations of LDL and triglycerides and elevating the concentration of HDL

The vial has been consistently refrigerated except for brief removal during dose preparation

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Once reconstituted, store at 2 to 8 degrees Celsius (standard refrigerator temperature) and use within the recommended timeframe

For patients who frequently miss doses despite reminder systems, discussing barriers with healthcare providers is essential