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Patients whose joint pain limits the exercise capacity needed to lose weight through lifestyle intervention alone a genuinely vicious cycle benefit particularly from a pharmacologic approach that produces meaningful loss independent of exercise capacity

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Semaglutide does not inherently cause thyroid dysfunction, but the rapid weight loss it enables can mobilize stored thyroid hormones, temporarily elevating TSH or free T4 levels

Sarda, F.A.H., Giuntini, E.B., Gomez, M.L.P.A., Lui, M.C.Y., Negrini, J.A.E., Taini, C.C., Lajolo, F.M., & Menezes, E.W

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Bariatric Surgery or GLP-1's: Which weight loss treatment is right for you