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McGraw-Hill / Lange rxlist.com (Onglyza ) Keywords Linagliptin Trade Name: Tragenta Drug Class: oral hypoglycemics Mechanism of Action: An inhibitor of dipeptidyl peptidase-4 (DPP-4), a protease that degrades the incretin GLP-1 Pharmacokinetics: biliary tract excretion - unique elimination route amongst the DPP-4 inhibitors useful for Type II diabetic patients with reduced renal function

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STEP 5 Trial After 2 years, people still kept the weight offaround 15.2% weight loss, and over 60% lost at least 10% of their starting weight