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Time to weight plateau with tirzepatide treatment in the SURMOUNT1 and SURMOUNT4 clinical trials

Semaglutide is found in other popular weight loss medications, including Ozempic, but Wegovy contains higher doses

Data are least squares mean (standard error) from mixed-model repeated measures for change in A ) pre-lunch appetite VAS scores, B ) Food Craving Inventory, C ) Food Craving Questionnaire-State, D ) Eating Inventory, and E ) Power of Food Scale, at week 3 in all randomized participants (placebo, n = 39

Significant weight loss may cause temporary effects such as loose skin or fatigue gradual, supervised progress reduces risks

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In SURPASS-2, which compared tirzepatide to semaglutide 1 mg in 1,879 patients with type 2 diabetes, tirzepatide 5 mg, 10 mg, and 15 mg reduced systolic blood pressure from baseline by 5.6, 7.4, and 8.0 mmHg respectively at 40 weeks, compared to 5.3 mmHg with semaglutide