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Even though additional physicochemical properties play important roles, placental transfer of drugs with such high molecular size is generally not anticipated in the first trimester of pregnancy, unless a specific mechanism for transfer exists
Thomas is with the Creighton University School of Medicine in Phoenix, Arizona
Am J Obstet Gynecol (1996) 174(6):185561
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[DOI] [PubMed] [Google Scholar] Toft-Nielsen MB, Madsbad S, Holst JJ
