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This happens because rapid fat loss also reduces the deep support structures under the skin

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("Viking") (NASDAQ: VKTX), a clinical-stage biopharmaceutical company focused on the development of novel therapies for metabolic and endocrine disorders, today announced that new clinical data from the company's VK2735 obesity program were highlighted in a poster presentation at ObesityWeek 2025, the annual meeting of The Obesity Society

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Generally mild, but it is a new signal

95% CI: 0.321.00), though no significant effect was found on all-cause mortality (HR 0.81