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By May 2025, GLP-1s accounted for 52% of all diabetes prescription volume, up from just 18% in 2020

Your first meal sets the pace.

Heart failure with preserved ejection fraction (HFpEF) is the most common form of HF, especially among people with obesity

Zooming out, the obesity market is now clearly split across modalities: Novo Nordisk still anchors the peptide side with semaglutide, while oral small molecules are accelerating (orforglipron, elecoglipron and Roches Carmot deal)

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Anyone who wants to understand the decision logic behind building a three-compound stack before making moves that make the protocol harder to read rather than easier
