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Methods Scoping Review This is a scoping literature review on the extent of research on the combined use of GLP1-RAs and SGLT2is in individuals with T2D

Dopamine regulation and brain mechanisms One of the most significant findings across studies is the influence of GLP-1 receptor agonists on dopamine regulation

The patient population is enormous, fueled by direct-to-consumer advertising, word of mouth, social media, said Louis Zollo, national pharmacy practice leader and VP at Segal, a benefits consulting firm

When asked why, the most common reasons cited included not knowing enough about the long-term side effects of these drugs (49%), these medications being overused (32%), beliefs that weight loss should be managed by lifestyle not medication (29%), and feeling that the people who really need these medications arent getting them because too many people are using them for purely cosmetic purposes instead of health reasons (21%)

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Dry mouth, fatigue, nausea