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If you have severe gastrointestinal diseases like gastroparesis and inflammatory bowel disease, you should not take GLP-1 medicines

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Regarding other parameters, namely HbA1c levels and cardiovascular risk, it remains to be seen whether there is a sex difference

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What is critical is that the side effect profiles of these medications are generally very acceptable

5.3 GLP-1s anti-inflammatory effects GLP-1 receptor agonists significantly reduce inflammation by modulating immune cell activity and suppressing the release of pro-inflammatory cytokines, such as TNF- , IL-6, and IL-1 (99101)