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This article explores why taste changes may occur with semaglutide and provides practical guidance for managing this side effect

What were the cardiovascular signals

Side effect profile comparison In general, semaglutide has a slightly milder GI side effect profile compared to tirzepatide

It also states that, if needed for weight management in adult patients with obesity, the dose can be increased to 7.2 mg once weekly after a minimum of four weeks on 2.4 mg, using three 2.4 mg injections, with dose escalation delayed or reduced if significant gastrointestinal symptoms occur

The LV may also have features of noncompaction cardiomyopathy, further contributing to myocardial dysfunction