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Behavioural profile of exendin-4/naltrexone dose combinations in male rats during tests of palatable food consumption

Cocaine exposure is likely a critical component in this scenario, given the previous findings of minimal effects of exendin-4 on accumbens MSN firing in drug-nave rats [134] combined with recent studies showing increased frequency of MSN action potential firing in the nucleus accumbens core and shell in cocaine-experienced rats [132]