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This aligns with the hypothesis that greater weight loss leads to superior cardiovascular benefits, reinforcing the potential of Tirzepatide in hypertensive patients with obesity

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Novo Nordisk has announced headline results from the STEP UP study, a phase 3b trial in the global STEP programme, which revealed the trial achieved its primary endpoint by demonstrating a statistically significant and superior weight loss at week 72 with semaglutide 7.2mg versus placebo.STEP UP is a 72-week efficacy and safety trial investigating subcutaneous semaglutide 7.2mg compared to semaglutide 2.4mg and placebo, all administered once weekly