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GLP-1 drugs also slow down how fast the stomach empties, reduce appetite, and lead to weight loss
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doi: 10.1136/bmj.327.7414.557 27 HemaniGZhengJElsworthBWadeKHHaberlandVBairdDet al
For compound 2, truncation of a large portion (28-48 residues) of the N-terminal -helix resulted in a dramatic efficacy decrease of compound 2, implying the role of the tip of N-terminal -helix in the ago-allosterism
