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Reduces appetite aids weight loss Common Drugs (Examples) Exenatide Liraglutide Dulaglutide Semaglutide Lixisenatide Clinical Uses Type 2 Diabetes Mellitus (as monotherapy or combination) Obesity / weight management (especially semaglutide, liraglutide) Cardiovascular benefit: reduces major adverse CV events in T2DM with CVD Administration Subcutaneous injection (daily or weekly depending on formulation) Oral semaglutide available for some patients Adverse Effects Gastrointestinal: nausea, vomiting, diarrhea Risk of pancreatitis (rare but serious) Mild hypoglycemia if combined with sulfonylureas or insulin Injection site reactions Contraindications / Precautions Personal/family history of medullary thyroid carcinoma History of multiple endocrine neoplasia syndrome type 2 (MEN2) Severe gastrointestinal disease (gastroparesis) GLP-1 agonists = incretin mimetics

Easy for your gut to digest and absorb, it delivers beneficial metabolites straight to your digestive tract, where they can immediately begin working to build a healthy gut microbiome.

Leslie Gammon used telehealth services to obtain GLP-1 medication for weight loss

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PlexusDx provides personalized semaglutide options with genetic insights to support safe weight management alongside inflammatory bowel condition care

Dietitian Connection webinar: Are GLP-1s a double-edged syringe