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Glucagon-like peptide-1 (GLP-1) is a natural hormone released in the intestines to regulate blood sugar levels and metabolism

Multivariate analysis showed no difference between placebo and liraglutide arms in HbA1c at 6 months (HbA1c:0.2mmol/mol, 11.3, 11.6, p=0.98) however, at 12 months HbA1c was significantly higher in the liraglutide arm (HbA1c:10.9mmol/mol, 1.1, 20.6, p=0.032)

Obesity management: Used widely for weight loss, even in non-diabetic individuals

Another systematic review of randomized trials found that muscle-related indices often exceeded the usual benchmark of about 25% of weight loss coming from fat-free mass

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