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GFJ significantly reduced the major metabolite of amiodarone [i.e., N -desethylamiodarone, N-desethylamiodarone (N-DEA)] production in all subjects, increasing AUC and Cmax by 50% and 84%, respectively, compared to water administration

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Mean body weight change of negative 14.9 percent for semaglutide vs negative 2.4 percent for placebo
