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Competing Interests Blair Suter, Allison Bigeh, Timothy Frommeyer, and Laxmi Mehta declare that they have no conflicts of interest

Natural GLP-1 production, while essential for normal glucose homeostasis, is insufficient to treat established metabolic disease

Each system is evaluated with explicit attention to the evidence supporting biological relevance, the reasons for historical underexploration, and the translational questions that must be addressed to enable renewed development

Employers (especially larger employers) tended to rate obesity closer to a chronic condition, while health plans leaned slightly toward the lifestyle view

The results showed that liraglutide reduced visceral fat while relatively increasing subcutaneous fat

S., Amaro A., and Wadden T