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Shankar et al., 2024)
It is synthesized after cell-specific post-translational processing by the prohormone convertases (Pcsk1) (Figure 1) [42,43]
Ligand-dependent modulation of G protein conformation alters drug efficacy

These effects are observed independently of glucose levels and weight loss (35)
It can also be prescribed for those who are overweight, with a BMI of 27 or higher, if they also have at least one weight-related health condition
Thalamic fibres project to the primary gustatory cortex in the insula, where taste qualities are further distinguished [3, 4]