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They function by mimicking hormones that control appetite and blood sugar, making people feel fuller

Introduction: Obesity is a global epidemic affecting 2.5 billion people and is recognized as the fourth leading cause of global mortality

There is increasing concern about the development of pancreatitis in patients with diabetes mellitus who received long-term glucagon-like peptide-1 (GLP-1) analog treatment

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The combination therapy of GLP-1 receptor agonists and metformin demonstrates superior safety over monotherapy, while revealing novel adverse events and demographic-specific risk patterns, thereby offering reliable evidence to inform clinical practice.

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