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However, its GLP-1-based mechanism of action could theoretically increase the risk of certain cancers [15]

GLP-1 might be more important for total appetite control, but GIPs contribution to the overall weight loss magnitude is clearly significant

Eli Lilly has pulled the plug on a Phase IIb trial that was testing the investigational antibody bimagrumab in combination with Zepbound to improve weight loss

Some patients find their side effect profile worsens at this level and choose to step back to 10mg for maintenance

Oral versions work similarly, though injectable formulations may have slightly different hydration considerations

Int J Mol Sci 2023;24:3206
