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Although there is no evidence supporting a correlation between genotype and body fat distribution or obesity, research has suggested that certain genetic mechanisms involving the MKRN3 and MAGEL2 genes, as well as Small Nucleolar RNAs, may play a role in controlling body weight (81, 156162)

Key Takeaways: Patients notice effects of GLP-1 medications like a reduced appetite within 12 weeks, though this can vary

Staying well hydrated in the 24 hours following injection also helps, as dehydration compounds tiredness significantly and is easy to slip into when appetite and thirst signals are both suppressed

The nicknames often come from their most prominent and publicized effects on health or behavior

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