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Feb 21, 2026 At the surface of nearly every cell in the human pancreas, a receptor waits

Pierret ACS, Mizuno Y, Saunders P, Lim E, De Giorgi R, Howes OD, McCutcheon RA, McGowan B, Sen Gupta P, Smith D, Ismail K, Pillinger T (2025) Glucagon-Like Peptide 1 Receptor Agonists and Mental Health: A Systematic Review and Meta- Analysis

Pharmacological treatment of obesity is associated with post-cessation weight regain or weight cycling a further concern in the context of sarcopenia

Clinical Impact: Clinical studies and patient observations have shown that GLP-1 agonists can lead to substantial weight loss in individuals with severe obesity, including those with genetic syndromes like BBS

Past performance does not guarantee future results

Methods References for the review were identified through PubMed searches for articles and reviews published from January 2013 to December 2024, although older references were used when appropriate