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When calorie intake declines, the body adapts by lowering total energy requirements, which can include modest reductions in lean tissue. Mechanical load and mechanotransduction Skeletal muscle depends on mechanical stress to maintain size and strengtha process governed by mechanotransduction . Example : If a person weighs 250 lb, their muscles perform constant load-bearing work

34.9% women) included in the review, 23 reported on incidence of dementia or cognitive impairment

[DOI] [PMC free article] [PubMed] [Google Scholar] 129.McClean PL, et al

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(A link to the article is included in the downloadable course document)