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68 In contrast, other large-scale population-based studies have failed to demonstrate a significant increase in intestinal obstruction risk when GLP-1 RAs were compared with SGLT-2 inhibitors

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A 2021 randomized controlled trial demonstrated that exenatide, a GLP-1 receptor agonist, significantly slowed cognitive decline in patients with early-stage Parkinsons disease compared to a placebo group (Athauda et al., 2021)

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Down 45 pounds and my A1C improved too

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However, retatrutide has not received FDA approval

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