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GLP-1 therapy can cause temporary fatigue as your body adapts to appetite suppression and metabolic changes

Zooming out, the obesity market is now clearly split across modalities: Novo Nordisk still anchors the peptide side with semaglutide, while oral small molecules are accelerating (orforglipron, elecoglipron and Roches Carmot deal)

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That meant looking for small molecules that unlike peptides can be more readily absorbed into the bloodstream