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Initially intended to control blood glucose levels in patients with type 2 diabetes, semaglutide, a potent glucagon-like peptide 1 analogue, has been established as an effective weight loss treatment by controlling appetite

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Adolescents and young adults are increasingly using GLP-1 receptor agonists for weight management, raising concerns among some dermatologists who may also prescribe a teratogenic drug like isotretinoin for acne

Amongst, overweight and obese patients defined by BMI in 2024 (58.9% [95% CIs 53.3-64.2%] female [182/309], median [IQR] age 56.6 [46.2-66.1]) GLP 1RA use has increased from 3.2% (10/309 [95% CIs 1.8-5.9%]) to 13.6% (42/309 [95% CIs 10.2-17.9%] [p=7.1x10-6])

Explore Retatrutide UK, a triple receptor agonist research peptide investigated for its interaction with GLP-1, GIP and glucagon metabolic signalling pathways.

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