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Trehalose and mannitol serve as effective cryoprotectants, while phosphate buffers maintain pH stability throughout processing

Read the full Government Press Release here

But pretending cost does not factor into the decision would be equally wrong

That gap matters more than most people realize

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In addition to the original R1 formulation of 3, 7 and 14mg, there is now a more conservative R2 dosing formulation of 1.5, 4 and 9mg