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NICE DSU Technical Support Document 3: Heterogeneity: Subgroups, Meta-Regression, Bias And Bias-Adjustment
[DOI] [PMC free article] [PubMed] [Google Scholar] 27.McLean B.A., Wong C.K., Campbell J.E., Hodson D.J., Trapp S., Drucker D.J
The mechanism of action involves mimicking two naturally occurring incretin hormones
While both are effective, Tirzepatide has shown slightly higher average weight loss in clinical trials, which contributes to its premium pricing in both brand-name and compounded forms
Common side effects include gastrointestinal issues, which typically decrease over time
In clinical trials, participants have reported: These effects are similar to those seen with other medications targeting GLP-1 pathways
