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The patient should continue semaglutide while initiating first-line RLS treatment with alpha-2-delta ligands (gabapentin, gabapentin enacarbil, or pregabalin...

patients had CKD stages 1 to 5 diagnosed by Kidney Disease: Improving Global Outcomes guidelines plus at least 3 months of one of the following: moderate to severe albuminuria regardless of estimated glomerular filtration rate (eGFR), eGFR less than 90 mL/min/1.73 m2 with structural abnormalities of the kidney or urinary sediment abnormalities, or eGFR less than 60 mL/min/1.73 m2

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muciniphila are interesting candidates as they can potentially reach and interact with the epithelial barrier

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