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Furthermore, GLP-1 is produced by a small group of neurons in the nucleus tractus solitarius (NTS) in the caudal brainstem and released as a neuromodulator within the brainstem and hypothalamus (11)

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Injection form release gradually semaglutide and ensures sustainable effect over time

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doi: 10.1136/bmjdrc-2019-000904

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Of note, the dopamine neurons in the ARH also regulate pituitary hormones (71), which could be linked to the GLP-1 stimulatory release of pituitary hormones, such as vasopressin and corticotropin-releasing hormone (72)

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But knowing when to adjust medication versus when to adjust behavior requires data, not guesswork

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What should I do if I feel severe nausea on injection day despite eating small meals

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