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The inflammation piece is where things get more interesting

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Tirzepatide is a new drug targeting glucagon-like peptide 1(GLP1) and gastric inhibitory polypeptide (GIP) receptors

What the 2025 Expert Consensus Found Using a Delphi process with 58 experts from 17 countries, the panel reviewed available evidence and reached key agreements: 1

There is a unique opportunity for collaboration across specialties to raise awareness around the multiple benefits of GLP-1 RAs and determine the best care pathway to treat patients with PAD. With the ongoing PAD amputation and obesity epidemics, there is an opportunity to establish partnership and open communication between vascular surgeons and weight loss clinics to determine if a patient could benefit from GLP-1 RAs. i Molina CS, Faulk JB