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Recent Findings Results from CV outcomes trials have demonstrated the efficacy of GLP-1 RA and dual GLP-1/GIP receptor agonists to promote weight loss and improve CV outcomes across diverse populations, including reduced risk of major adverse CV events and mortality, progression of chronic kidney disease, as well as improvements in quality of life and functional status

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In the adipose tissue, LDs respond to nutrient fluctuations by modulating lipolysis and releasing free fatty acids (FFAs) and glycerol