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It belongs to a class of drugs called incretin mimetics, but unlike existing medications (semaglutide targets one hormone pathway, tirzepatide targets two), retatrutide activates three metabolic receptors : GLP-1, GIP, and glucagon

Recently, agonists of glucagon-like peptide-1 (GLP-1) receptor, designed based on the gut hormone GLP-1, have been developed as anti-obesity drugs and have demonstrated remarkable efficacy in treating both obesity and diabetes

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However, compounded medications are not FDA-approved as finished products

Unregulated or black-market semaglutide and tirzepatide may contain incorrect doses, impurities, or counterfeit formulations that can cause severe complications including pancreatitis, gallbladder disease, thyroid changes, or allergic reactions

It also discusses the fact that both oral tablets and injections have been found effective in facilitating weight loss and explores the differences between these medications