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The bile acid receptor Fxr is a modulator of intestinal innate immunity

In SURMOUNT-1, the 15 mg group lost an average of 20.9% body weight over 72 weeks
Owing to its pronounced effects on body-weight reduction, glycemic regulation, and attenuation of systemic inflammation, GLP-1RAs have attracted growing interest as potential modulators of cancer-relevant biological pathways
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