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Health Canada is warning people not to buy or use fake or unauthorized versions of GLP-1 drugs such as semaglutide, the active ingredient in Ozempic and Wegovy

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The use of glucagon-like peptide-1 receptor agonists (GLP-1RAs), used to treat diabetes and obesity, may be associated with a wide range of health effects, both positive - such as a reduced risk of cardiometabolic disorders - and negative - an increased risk of gastrointestinal conditions or hypertension

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The weight loss market is undergoing a seismic shift as the focus moves from injectable peptides to oral small molecule GLP-1 receptor agonists, led by Eli Lillys promising candidate, orforglipron

The intestine has garnered attention as a target organ for developing new therapies for impaired glucose tolerance