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Similarly, tirzepatide glycine combinations and tirzepatide with B12 are popular compounded options

Emerging research suggests GLP-1 medications may affect more than blood sugar and body weight

Additionally, similar to CVD (145, 146), it appears that the combination of GLP-1 mimetic with SGLT-2 inhibitor may too be beneficial with regards to cognition, with DIO/STZ-mice receiving liraglutide/SGLT-2 combination therapy presenting with improved recognition and hippocampal morphology (160)

This response was measured through functional magnetic resonance imaging (fMRI)

B12 deficiency can mimic GLP-1 side effects like fatigue and brain fog, making it difficult to distinguish medication effects from nutritional deficiency without testing
