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Studies indicate that GLP-1R activation exerts anti-inflammatory effects on macrophages, reduces endothelial dysfunction, and inhibits smooth muscle proliferation

By Patricia Van Arnum, Editorial Director, DCAT, [email protected] Whats next Glucagon-like peptide 1 (GLP-1) agonists, used to treat Type 2 diabetes and obesity, have been a success story in the industry, with Novo Nordisk riding a blockbuster wave with Ozempic/Wegovy (semaglutide), respectively for treating Type 2 diabetes and obesity, and Eli Lilly and Company also riding the wave with Mounjaro/Zepbound (tirzepatide), a dual-activating GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 medication, respectively for treating Type 2 diabetes and obesity

This modular strategy could help manufacturers leverage the advantages of a well-established process (SPPS) while minimizing its operational risks

Looking at specific age groups, researchers found that nearly 19% of those 50 to 64 had tried a GLP-1 drug, compared to 13% of those 65 and older and 11% of those 30 to 49

Patients should explore their coverage options and discuss affordability with their healthcare provider before starting treatment

Consider contacting the Poison Help line (1-800-222-1222) or a medical toxicologist for additional overdose management recommendations