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This limits our ability to determine whether diabetes itself constitutes an independent risk factor for adverse gastrointestinal outcomes with these agents

Because of these concerns, it is essential for clinicians to screen for eating disorders before prescribing GLP-1RAs in individuals with overweight or obesity

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Orforglipron, Lilly's once-daily oral non-peptide GLP-1 agonist, helped overweight adults without diabetes lose 12.4% of their body weight over 72 weeks at the highest dose in a late-stage trial

(b) Representative micrographs of Fos (in red) and TH+ (in green) neurons in the cNTS after nicotine (0.25-1.5 mg/kg) injection

Do GLP-1s help inflammation