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After six months of empagliflozin treatment, the patients glycemic control significantly improved: HbA1c levels decreased from 7.4% to 6.2% and TIR increased from 61% to 91%

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We assessed the risk of a composite kidney outcome, including confirmed 40% eGFR loss or end-stage kidney disease, and the risk of new macroalbuminuria

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However, Manon underwent the same enrollment process as anyone else: She started by filling out a medical intake form, then she got some lab tests done

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Adult obesity and type 2 diabetes

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Mutants and transgenic worms are listed in Supplementary Table S1

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