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A retrospective analysis of more than 110,000 women between the ages of 45 and 80 found that those who take GLP-1 medications are about 30% less likely to develop breast cancer than those who do not take GLP-1 medications.

While effective and free of hepatotoxicity, high rates of nausea (70%) and vomiting (67-69%) pose challenges for global studies

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Conclusions To conclude, reduced Cmax and delayed tmax of drugs co-administered with GLP1RAs are consistent with the known delayed gastric output by the latter

Unexpected signals included kidney injury and pancreatic cancer