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5.4 Gastrointestinal Side Effects and Nutrient Loss Nausea and vomiting are well-documented adverse effects. Persistent vomiting or diarrhoea may: Increase electrolyte loss Reduce caloric intake Reduce dietary diversity However: These effects are typically transient and dose-related

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GLP-1 receptors exist in brain regions involved in attention and impulse control, but this does not establish clinical efficacy for ADHD

This was a key step toward determining whether an incretin such as GLP-1i.e

These organs are all therefore potential sites of alerted signalling if endogenous fetal GLP-1 levels are altered, or if GLP-1 signalling is over-activated by exposure to GLP1RAs during fetal development