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J., Chen, N., Makhijani, P., Winer, S., Furman, D., & Winer, D

Circulation (2008) 117:234050

This setup, combined with early input from process chemists, helps avoid scalability pitfalls

Most side effects are mild to moderate and resolve within the first 4 to 6 weeks

The absolute net benefit of attaining 10% weight loss without experiencing worrisome harms over 2 years was equivalent to 104 (95% CI, 100-112) per 1,000 people, Moll and colleagues reported

These are powerful drugs that need careful use, but with proper supervision they could be a valuable tool in tackling our obesogenic, ultra-processed food environment