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The trade-off was injection site reactions (small nodules) in some patients, since the microspheres reside under the skin for weeks

doi: 10.1056/NEJMoa2108269 86 HernandezAFGreenJBJanmohamedSDAgostinoRBGrangerCBJonesNPet al

On the other hand, gastric emptying is not considerably impacted by glucose-dependent insulinotropic polypeptide (GIP), emphasizing the distinct functions of these incretins in GI function ( A study examined the potential advantages and disadvantages of using GLP-1RAs to help obese but non-diabetic patients lose weight

2 Transformative therapeutics Lotte Bjerre Knudsens work at Novo Nordisk marked a pivotal transition from scientific discovery to clinical application

Furthermore, direct comparisons of analogues of these two incretins often resulted in more favourable outcomes for GLP-1 compared to GIP (129)

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