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S., Pharmacotherapy of Obesity: An Update on the Available Medications and Drugs Under Investigation, EClinicalMedicine 58 (2023): 101882, 10.1016/j.eclinm.2023.101882

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The glia may play a critical role in the central nervous system inflammatory responses including Alzheimer's disease, and GLP-1 receptor was observed in astrocytes and microglia [17, 87]

In patients in whom development of renal dysfunction is anticipated, particularly in elderly patients, renal function should be assessed more frequently and JANUMET discontinued if evidence of renal impairment is present

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further exacerbating the appearance of sagging and ageing
