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The A Study of Tirzepatide on the Reduction on Morbidity and Mortality in Adults with Obesity (SURMOUNT-MMO) trial assesses tirzepatide's impact on mortality and cardiovascular events in overweight or obese individuals

"Based on our study, we recommend that guidelines be updated with the following precautions for GLP-1 RA users undergoing endoscopic procedures: continue therapy, follow a liquid-only diet the day prior, and adhere to standard pre-anaesthesia fasting," said lead author, Dr Brent Hiramoto, senior gastroenterology Fellow at Brigham and Women's Hospital
Long-acting human GLP-1 drugs will be the main force in the diabetes market in the future
Switching recommendations for patients taking OZEMPIC 0.25 mg, 1 mg or 2 mg subcutaneously once weekly to RYBELSUS (formulation R1) are not available

Aronne LJS, Horn N, He DBB, et al

The circulating concentrations of GLP-1 RA activity are much higher than physiological levels of GLP-1 activity (22)
