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Short-acting GLP-1 RAs, exenatide and lixisenatide, are associated with a transient (112 h) mean placebo- and baseline-adjusted 24-h HR increase of 13 beats per minute (bpm)

While challenges with adherence, side effects, and weight regain upon discontinuation have prompted the search for additional strategies, targets like GLP-1R, GIPR, and GDF8 (Myostatin) still remain the most highly relevant and active areas of research for developing effective obesity treatments

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In fact, your focus needs to be on weight training so you can keep muscle and maintain a healthy metabolism.