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Patients should report severe or persistent nausea, vomiting, abdominal pain (especially if radiating to the back, which may indicate pancreatitis), right upper quadrant pain (possible gallbladder disease), or signs of allergic reaction

Most people report stable appetite reduction, fewer cravings for processed foods, and a natural shift toward smaller, more satisfying meals

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In individuals with low BMI, this imbalance causes subtle depressions, but as BMI increases, fat lobules expand, and septal tension is further disrupted, worsening the dimpling

Effects on cholecystokinin and other gastrointestinal hormones may influence gallbladder contraction patterns