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Similarly, some authors observed that metformin users had a lower clinical severity of TC at presentation and a longer disease free survival in metastatic patients (Jang et al., 2015), while other authors did not observe any difference in the risk of developing metastases when compared with non-treated patients (Noh et al., 2019)

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MarxNRosenstockJKahnSEZinmanBKasteleinJJLachinJMet al

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Jebeile H, Gow ML, Baur LA, Garnett SP, Paxton SJ, Lister NB